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| Suffix | Category | Example |
|---|---|---|
| -actide | ACTH analog | Tetracosactide |
| -afil | PDE-5 inhibitor | Sildenafil |
| -alkeran | Nitrogen mustard alkylator | Melphalan |
| -ane | Inhaled anesthetic | Halothane |
| -anserin | 5-HT2 antagonist | Ketanserin |
| -anserin | 5-HT2 antagonist | Ketanserin |
| -asvir | NS5A inhibitor | Ledipasvir |
| -azepam | Benzodiazepine | Diazepam |
| -azepam | Benzodiazepine | Diazepam |
| -azine | Typical antipsychotic | Thioridazine |
| -barbital | Barbiturate | Phenobarbital |
| -bendazole | Antiparasitic/antihelminthic | Mebendazole |
| -buvir | NS5B inhibitor | Sofosbuvir |
| -cainide | Antiarrhythmic | Flecainide |
| -cainide | Antiarrhythmic | Flecainide |
| -caine | Local anesthetic | Lidocaine |
| -case | Recombinant uricase | Rasburicase |
| -cept | Receptor fusion protein | Etanercept |
| -ciclib | CDK4/6 inhibitor | Palbociclib |
| -cillin | Transpeptidase inhibitor | Ampicillin |
| -conazole | Ergosterol synthesis inhibitor | Ketoconazole |
| -curium | Nondepolarizing paralytic | Atracurium |
| -curonium | Nondepolarizing paralytic | Vecuronium |
| -cycline | Protein synthesis inhibitor | Tetracycline |
| -dipine | Dihydropyridine CCB | Amlodipine |
| -dralazine | Antihypertensive | Hydralazine |
| -dralazine | Antihypertensive | Hydralazine |
| -dronate | Bisphosphonate | Alendronate |
| -etine | SSRI | Fluoxetine |
| -etidine | Neuroleptic | Spiperone |
| -etidine | Neuroleptic | Spiperone |
| -fenine | Analgesic | Antipyrine |
| -fenine | Analgesic | Antipyrine |
| -floxacin | Fluoroquinolone | Ciprofloxacin |
| -gestrel | Progestin | Levonorgestrel |
| -gestrel | Progestin | Levonorgestrel |
| -gliflozin | SGLT2 inhibitor | Canagliflozin |
| -gliptin | DPP-4 inhibitor | Sitagliptin |
| -glitazone | Thiazolidinedione | Pioglitazone |
| -glutide | GLP-1 receptor agonist | Liraglutide |
| -ipramine | Tricyclic antidepressant | Imipramine |
| -isone | Corticosteroid | Prednisone |
| -isone | Corticosteroid | Prednisone |
| -kinra | IL-1 receptor antagonist | Anakinra |
| -lukast | Leukotriene receptor antagonist | Montelukast |
| -mivir | Neuraminidase inhibitor | Oseltamivir |
| -mustine | Nitrosourea | Carmustine |
| -mycin | Macrolide or aminoglycoside antibiotic | Erythromycin |
| -mycin | Macrolide or aminoglycoside antibiotic | Erythromycin |
| -navir | Protease inhibitor | Ritonavir |
| -nidazole | Nitroimidazole antimicrobial | Metronidazole |
| -nidazole | Nitroimidazole antimicrobial | Metronidazole |
| -nonium | Neuromuscular blocker | Pancuronium |
| -nonium | Neuromuscular blocker | Pancuronium |
| -olol | Beta-blocker | Propranolol |
| -ovir | Viral DNA polymerase inhibitor | Acyclovir |
| -peridol | Antipsychotic | Haloperidol |
| -peridol | Antipsychotic | Haloperidol |
| -piride | Prokinetic / Antipsychotic | Metoclopramide |
| -piride | Prokinetic / Antipsychotic | Metoclopramide |
| -platin | Platinum compound | Cisplatin |
| -poside | Topoisomerase II inhibitor | Etoposide |
| -previr | NS3/4A inhibitor | Grazoprevir |
| -pramide | GI prokinetic | Metoclopramide |
| -pramide | GI prokinetic | Metoclopramide |
| -pril | ACE inhibitor | Lisinopril |
| -profen | NSAID | Ibuprofen |
| -profen | NSAID | Ibuprofen |
| -prost | Prostaglandin analog | Latanoprost |
| -prost | Prostaglandin analog | Latanoprost |
| -rubicin | Anthracycline | Doxorubicin |
| -rudin | Direct thrombin inhibitor | Bivalirudin |
| -sartan | Angiotensin II receptor blocker | Losartan |
| -serin | Serotonin receptor agent | Ketanserin |
| -serin | Serotonin receptor agent | Ketanserin |
| -spirone | Aldosterone antagonist | Spironolactone |
| -spirone | Aldosterone antagonist | Spironolactone |
| -statin | HMG-CoA reductase inhibitor | Atorvastatin |
| -stigmine | AChE inhibitor | Neostigmine |
| -suximide | Antiepileptic | Ethosuximide |
| -suximide | Antiepileptic | Ethosuximide |
| -taxel | Taxane | Paclitaxel |
| -tecan | Topoisomerase I inhibitor | Irinotecan |
| -tegravir | Integrase inhibitor | Dolutegravir |
| -terol | Beta2 agonist | Albuterol |
| -thiazide | Thiazide diuretic | Hydrochlorothiazide |
| -thiazide | Thiazide diuretic | Hydrochlorothiazide |
| -thromycin | Macrolide | Azithromycin |
| -tinib | Tyrosine kinase inhibitor | Imatinib |
| -triptan | 5-HT1B/1D agonist | Sumatriptan |
| -triptiline | Tricyclic antidepressant | Amitriptyline |
| -triptiline | Tricyclic antidepressant | Amitriptyline |
| -tropium | Muscarinic antagonist | Ipratropium |
| -vaptan | Vasopressin receptor antagonist | Tolvaptan |
| -vaptan | Vasopressin receptor antagonist | Tolvaptan |
| -xaban | Factor Xa inhibitor | Rivaroxaban |
| -zepam, -zolam | Benzodiazepine | Diazepam, Alprazolam |
| -zomib | Proteasome inhibitor | Bortezomib |
| -zosin | Alpha1 antagonist | Prazosin |
| Drug | Class | Indication | ADRs | Notes |
|---|---|---|---|---|
| Antibodies | ||||
| Alemtuzumab | anti-CD52 mAb | CLL, MS | — | “52 cards in a deck → drink Ale” |
| Bevacizumab | anti-VEGF mAb | Metastatic CRC, NSCLC, RCC | — | “Vacuum packing vegetables down your butt” |
| Cetuximab | anti-EGFR mAb | Colon and head & neck cancers | — | “CET = Colon, EGFR, Throat” |
| Rituximab | anti-CD20 mAb | Non-Hodgkin lymphoma, CLL | — | “NHL 20 cover = guy in TUXedo |
| Trastuzumab | anti-HER2 mAb | HER2+ breast cancer | — | “Tras-2-zumab → Hurts you” |
| Infliximab | anti-TNF-α mAb | Autoimmune diseases (RA, Crohn's, UC) | — | “INFLIX damage during inflammation” |
| Daclizumab | anti-CD25 mAb | Multiple sclerosis | — | “#25 Ben Simmons MONSTER SMASH (DAC)” |
| Eculizumab | anti-C5 complement mAb | Paroxysmal nocturnal hemoglobinuria | — | “E-cul car w/ Pretty Nice Head” |
| Natalizumab | anti-α4-integrin mAb | MS, Crohn’s | — | “TAILs & 4 legs → Multiple Species” |
| Ustekinumab | anti–IL-12/IL-23 mAb | Psoriasis | — | “Used to be 12, now 23” |
| Abciximab | anti–GPIIb/IIIa mAb | Antiplatelet (PCI) | — | “ABC = IIb/IIIa = 2×3 = 6” |
| Denosumab | anti-RANKL mAb | Osteoporosis | — | "Deno socks on your rANKLe” |
| Omalizumab | anti-IgE mAb | Allergic asthma | — | “Ig8 = #18 = Peyton Manning = Omaha” |
| Palivizumab | anti–RSV F protein mAb | RSV prophylaxis | — | “Pali-o diet → Really Simple Vegetarians” |
| Tocilizumab | anti–IL-6 receptor mAb | RA, cytokine release syndrome | — | “Silly 6 yr olds” |
| Canakinumab | anti–IL-1β mAb | Periodic fever syndromes | — | |
| Belimumab | anti–BAFF mAb | SLE | — | |
| Secukinumab | anti–IL-17A mAb | Plaque psoriasis, ankylosing spondylitis | — | |
| Ixekizumab | anti–IL-17A mAb | Plaque psoriasis | — | |
| Dupilumab | anti–IL-4Rα mAb | Atopic dermatitis, asthma | — | |
| Biologics & Fusion Proteins | ||||
| Abatacept | CD80/86 fusion protein | RA, autoimmune conditions | — | “aBaTacept intercepts B-cell activation by T-cells” |
| Vemurafenib Dabrafenib Encorafenib |
BRAF V600E kinase inhibitors | Late-stage melanoma (BRAF V600E+) | — | “vemuRAFenib” |
| Palbociclib | CDK4/6 inhibitor | Metastatic breast cancer | — | “Pablo rode his biCYCLE from 4-6 most (mets) days” |
| Antibiotics | ||||
| Cell Wall | ||||
| Cefazolin | 1st gen Cephalosporin | Surgical prophylaxis | Hypersensitivity | |
| Cefuroxime | 2nd gen Cephalosporins | Gram-negative infections | Disulfiram rxn (cefotetan) | |
| Cefotetan | 2nd gen Cephalosporins | Gram-negative infections | Disulfiram rxn (cefotetan) | |
| Cefoxitin | 2nd gen Cephalosporins | Gram-negative infections | Disulfiram rxn (cefotetan) | |
| Cefotaxime | 3rd gen Cephalosporins | Severe Gram– infections | Hypersensitivity | |
| Ceftazidime | 3rd gen Cephalosporins | Severe Gram– infections | Hypersensitivity | |
| Cefepime | 4th gen Cephalosporin | Pseudomonas, broad Gram– coverage | Seizures (high dose) | |
| Clavulanate | Beta-lactamase inhibitors | Combined with penicillins | GI upset | |
| Tazobactam | Beta-lactamase inhibitors | Combined with penicillins | GI upset | |
| Sulbactam | Beta-lactamase inhibitors | Combined with penicillins | GI upset | |
| Bacitracin | Cell wall inhibitor | Topical Gram+ skin infections | Nephrotoxicity (if systemic) | |
| Oxacillin | Penicillinase-resistant Penicillins | Staphylococcus aureus (non-MRSA) | Interstitial nephritis | |
| Nafcillin | Penicillinase-resistant Penicillins | Staphylococcus aureus (non-MRSA) | Interstitial nephritis | |
| Amoxicillin | Aminopenicillins | Broad-spectrum (HELPSS organisms) | Rash with EBV, diarrhea | |
| Ampicillin | Aminopenicillins | Broad-spectrum (HELPSS organisms) | Rash with EBV, diarrhea | |
| Piperacillin / Ticarcillin | Antipseudomonal Penicillins | Pseudomonas, Gram– rods | Same as penicillin | |
| Aztreonam | Monobactam | Gram– rods only | Generally safe | |
| Daptomycin | Lipopeptide | MRSA, VRE | Myopathy, CPK elevation | |
| Penicillin | Beta-lactam | Gram-positive infections | Allergic reactions | |
| Cephalexin / Ceftriaxone | Cephalosporins | Broad spectrum | Hypersensitivity | |
| Carbapenems | Beta-lactam | Serious infections | Seizures (rare) | |
| Vancomycin | Glycopeptide | MRSA | Red man syndrome | |
| Protein Synthesis | ||||
| Tobramycin | Aminoglycosides | Gram– rods, bowel prep | Ototoxicity, nephrotoxicity | |
| Neomycin | Aminoglycosides | Gram– rods, bowel prep | Ototoxicity, nephrotoxicity | |
| Erythromycin | Macrolides | Respiratory infections, MAC | QT prolongation, GI upset | |
| Clarithromycin | Macrolides | Respiratory infections, MAC | QT prolongation, GI upset | |
| Minocycline | Tetracyclines | Acne, SIADH (demeclocycline) | Photosensitivity, teeth staining | |
| Demeclocycline | Tetracyclines | Acne, SIADH (demeclocycline) | Photosensitivity, teeth staining | |
| Tigecycline | Glycylcycline | Complicated infections (MRSA, VRE) | GI upset, hepatotoxicity | |
| Quinupristin/Dalfopristin | Streptogramins | VRE, resistant Gram+ cocci | Myalgias, arthralgias | |
| Linezolid | Oxazolidinone | MRSA, VRE | Thrombocytopenia, serotonin syndrome | |
| Chloramphenicol | Protein synthesis inhibitor (50S) | Rickettsia, meningitis backup | Aplastic anemia, gray baby | |
| Gentamicin | Aminoglycoside | Gram-negatives | Nephrotoxicity, ototoxicity | |
| Doxycycline | Tetracycline | Broad spectrum | Photosensitivity | |
| Azithromycin | Macrolide | Respiratory infections | GI upset | |
| Clindamycin | Lincosamide | Anaerobic infections | C. difficile colitis | |
| DNA Inhibitors | ||||
| Rifabutin | Rifamycin | MAC prophylaxis (HIV) | Less CYP induction than rifampin | |
| Nitrofurantoin | DNA-damaging agent | Uncomplicated UTIs | Pulmonary fibrosis, GI upset | |
| TMP-SMX | Folate inhibitor combo | UTIs, PCP pneumonia | Hyperkalemia, sulfa allergy | |
| Antimycobacterial Agents | ||||
| Isoniazid (INH) | Mycolic acid synthesis inhibitor | TB treatment | Hepatotoxicity, neuropathy (B6 def) | |
| Ethambutol | Arabinogalactan synthesis inhibitor | TB treatment | Optic neuritis, red-green blindness | |
| Clofazimine | Unknown (leprosy agent) | Multibacillary leprosy | Skin discoloration | |
| Streptomycin | Aminoglycoside (30S) | 2nd line TB, plague | Ototoxicity, nephrotoxicity | |
| Ciprofloxacin | Fluoroquinolone | UTIs, GI infections | Tendon rupture | |
| Metronidazole | Nitroimidazole | Anaerobic infections | Disulfiram-like reaction | |
| Rifampin | Rifamycin | Tuberculosis | Orange body fluids | |
| Antivirals | ||||
| Herpes & CMV | ||||
| Coming soon... | ||||
| HIV | ||||
| Coming soon... | ||||
| Hepatitis | ||||
| Coming soon... | ||||
| Antifungals | ||||
| Azoles | ||||
| Coming soon... | ||||
| Polyene & Others | ||||
| Coming soon... | ||||
| Antiparasitics | ||||
| Protozoa | ||||
| Coming soon... | ||||
| Helminths | ||||
| Coming soon... | ||||